Are high-potency statins in low dose “strong statins”?
نویسندگان
چکیده
منابع مشابه
High-dose statins are cost-effective compared with conventional-dose statins in patients with acute coronary syndromes.
M e t h o d s Design: Cost-effectiveness study using a Markov decision-analysis model developed from 4 international, randomized, controlled trials with follow-up of 2 years (2 ACS trials, n = 8659, 77% men) or 5 years (2 stable CAD trials, n = 18 889, 81% men). Setting: United States. Patients: Hypothetical cohorts of 60-yearold patients with ACS or stable CAD. Intervention: High-dose (e.g., a...
متن کاملStatins in Chronic Kidney Disease- Are Statins Really Renoprotective
Numerous trials have shown that chronic kidney disease increases the risk of cardiovascular disease. Dyslipidemias have been shown to accelerate progression of kidney disease. Statins have assumed a pivotal role in management of hyperlipidemia. However their effect on renal function is still not fully understood. Some clinical trials have shown some renoprotective effect of statins but there is...
متن کاملHigh-dose statins should only be used in atherosclerotic strokes.
Statin therapy should not be initiated in this patient, a young woman free of vascular risk factors and at low risk for atherosclerotic cerebrovascular disease. Unfortunately, this patient has an iatrogenic stroke after a cardiac catheterization performed for symptoms described as “atypical.” There is no evidence that underlying atherosclerotic disease accounted for her cardiac symptoms or stro...
متن کاملAre statins anti-inflammatory?
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials than that expected on the basis of lipid lowering alone. Emerging evidence from both clinical trials and basic science studies suggest that statins have anti-inflammatory properties, which may additionall...
متن کاملCost-effectiveness of the use of low- and high-potency statins in people at low cardiovascular risk.
BACKGROUND Although statins have been shown to reduce the risk of cardiovascular events in patients at low cardiovascular risk, their absolute benefit is small in the short term, which may adversely affect cost-effectiveness. We sought to determine the long-term cost-effectiveness (beyond the duration of clinical trials) of low- and high-potency statins in patients at low cardiovascular risk an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Heart and Vessels
سال: 2012
ISSN: 0910-8327,1615-2573
DOI: 10.1007/s00380-012-0255-4